GE Future is Bright for New Zealand
Weekly Column by Dr Muriel Newman
This week the
Environmental Risk Management Authority, the independent
body that regulates genetic science, approved a genetic
engineering application by AgResearch, the Crown research
institute.
In effect, ERMA gave the go-ahead for
human and animal genes to be inserted into cows for the
purpose of producing therapeutic proteins in milk that could
be used in medical treatments. While the research has
widespread ramifications, people with the incurable disease
multiple sclerosis are seen to be a particular group who may
benefit.
ERMA took a cautious approach, taking double
the time allowed under the Hazardous Substances and New
Organisms Act to reach their decision. They also imposed
very strict controls on the project, reduced the timeframe
for the work and insisted that no genetically modified
material enter the food chain.
The application
process cost an estimated $500,000, far more expensive than
similar applications overseas. This is an issue of major
concern for a country that has a proud history of innovative
breakthroughs in science and medicine. Unless the cost of
applications becomes more reasonable, much GE research will
be out of reach of everyone except government agencies or
those in the private sector with the deepest of pockets.
As a result of ERMA’s decision to allow GE outside of
the laboratory, there has been an outcry from the ‘green’
lobby that this is the beginning of the end. They
conveniently choose to forget that humans have used
genetically modified animal products for generations.
Diabetics who cannot produce their own insulin have
used pig and cow insulin, found to be almost identical to
human insulin, for much of this century. Present day human
trials using transplanted cells from baby pigs are showing
new promise.
Major advances in the treatment of
diabetes were made in the 1980s through the production by
bacteria of genetically engineered human insulin. Sufferers
of cystic fibrosis, multiple sclerosis and human dwarfism
have all benefited from similar technologies in which human
genes are grown in bacteria. Similarly, a copy of the gene
for chymosin, a protein enzyme from the stomach of calves
which has been widely used in cheese making since the
eighties, is also grown in bacteria.
This history of
the widespread use of genetically modified medicines and
foods by humans shows that claims by the green lobby that
New Zealand is GE free are nonsense. GE has been in the food
chain for years, and while progress in GE should indeed
proceed with caution, it should nonetheless
proceed.
Fortunately, ERMA ignored the political
scaremongering of the radical green movement and instead
came up with a sensible decision that sends a signal to the
science community and to those investors who are seeking a
stake in the future, that New Zealand is forward-looking and
willing to embrace new technologies.
The reality is
that while information technology became the most
significant area of progress in the latter half of the last
century, it will be genetic engineering in this century. New
Zealand cannot afford to be left behind.
The benefits
of GE will be far-reaching and encompass all walks of life.
I recall a couple of years ago visiting a company that had
almost completed the gene mapping of pine trees. While they
believed that their research would be widely sought after
internationally, it was their next challenge that created a
groundbreaking opportunity for this Kiwi company. They were
working on the gene mapping of kauri trees in order to
isolate the gene that is responsible for kauri shedding
their branches.
Imagine what would happen if they
could successfully implant that kauri gene into pine trees
so that instead of needing to be pruned they simply shed
their branches? The move would revolutionise forestry,
putting New Zealand at the forefront of progress in that
industry.
As in most new fields of human endeavour GE
has the potential to create a future of opportunity that is
not only exciting and challenging, but will also produce
unimaginable benefits to consumers through lower prices,
greater choice, better services and an improved quality of
life.
ERMA’s decision to proceed with caution has
ensured that New Zealand has a stake in that future.