Kiwis involved in two ESR-led influenza studies are stepping up as part of the global research effort to better
understand the COVID-19 pandemic.
Two large-scale and long-term studies, SHIVERS-II and WellKiwis, will expand to include testing for SARS-CoV-2, the
virus that causes COVID-19.
The studies will take swabs and blood samples from participants to identify and follow up any COVID-19 infections.
ESR’s Principal Investigator of SHIVERS-II and WellKiwis, Dr Sue Huang says expanding the studies will help answer some
crucial scientific questions.
“Understanding the immunity and susceptibility of a population against COVID-19 is critically important to tailor public
health responses appropriately,” says Dr Huang.
“The comprehensive understanding of immune responses to COVID-19 will also inform effective vaccine development and
immune intervention treatment.
“Knowing the proportion of asymptomatic or mildly ill cases is important as it will help us to understand what is
driving this COVID-19 pandemic,” she says.
The studies will also expand to include the full households of those interested participants to provide important
information about the spread of COVID-19.
“The household is a valuable setting to understand the chain of transmission, the clinical spectrum of illness and the
amount and duration of virus being shed from infected individuals.
“This will inform public health measures in reducing the impact of the infection,” says Dr Huang.
The two studies follow Wellington adults and children over a number of years. SHIVERS-II focuses on adults’ immune
responses to the flu and flu vaccinations, while WellKiwis follows new-born babies to better understand how their first
flu exposure influences their ongoing immune responses to influenza.
“Globally there are very few studies of this kind. By taking part in these studies the participants are providing unique
platforms for comprehensive understanding of immune responses during the COVID-19 infection,” says Dr Huang.