Royal DSM, a global science-based company active in health, nutrition and sustainable living, is happy to announce a
well-advanced collaborative innovation program between New Zealand company Argenta, University of Otago and AgResearch
for the development of speciality forms of the methane inhibitor 3-NOP specific for the New Zealand market.
Mark van Nieuwland, global programme head for DSM says, “New Zealand dairy cow feeding systems mean that there is often a lag from the time the cows can consume a methane
inhibitor until the time they are back on pasture. Since 2017, we have therefore been working in New Zealand with
urgency on forms which will allow the inhibitor to remain active in the rumen for a prolonged period of time”.
Argenta, Otago University School of Pharmacy, and DSM Nutritional Products are providing numerous prototypes to be
evaluated by AgResearch Grasslands Research Centre in Palmerston North. Argenta is a New Zealand-based global animal
health company with expertise in slow release technology for ruminants and Otago University is a world leader in
designing speciality formulations.
Argenta has a long history of inventing and manufacturing products for animal health and specialises in controlled
release systems that work in the rumen of a sheep or cow, a skill highly relevant to this application. Dr Doug Cleverly,
co-founder of Argenta, comments: “The importance of selecting the right partners to resolve technical challenges at the invention step is critical, but
equally important is being able to handle commercial supply to New Zealand farms”.
Dr Greg Walker of Otago University adds: “Otago University has expertise in the targeted slow release of actives in the human health area and is very happy to
collaborate with industry on this challenge, to provide a formulation of 3-NOP which can enable farmers to reduce
methane emissions significantly”.
The collaboration has had promising outcomes from a first round of application trials late in 2018 and Dr Peter Janssen
of AgResearch comments: “In the first round of prototype testing a number of attractive options were found where 3-NOP reduced methane by over
30% for up to 6 hours after feeding the inhibitor. This could overcome the lag between the consumption of the inhibitor
on a feed pad or in-shed and subsequent access to pasture in paddocks where the majority of feed intake and therefore
methane production occurs”.
The partnership is now working through options around how the inhibitor could be used in dairy systems to maximise the
methane reduction over a full day. Mark van Nieuwland from DSM says that this second phase of product development is
refining the options toward a commercial formulation likely to become available next year, once regulatory requirements
are satisfied.
The feed additive 3-NOP has recently been recognised in a report by the World Resources Institute as one of the 10
breakthrough-technologies globally that can help feed the world without destroying it: https://www.wri.org/blog/2019/07/10-breakthrough-technologies-can-help-feed-world-without-destroying-it.