Emergency services are responding to a serious crash on Scotland Street (State Highway 8), Roxburgh, in Central Otago.
The two-car crash was reported just after 5pm.
The road is closed and diversions are in place at the intersections of SH 8 and Jedburgh Street, and SH 8 and Millers
Flat Bridge Road.
Motorists are asked to avoid the area if possible.
The Serious Crash Unit will attend the scene.