State Highway 49 near Rangataua Road, just out of Ohakune, is currently blocked.
Emergency services were notified that a truck carrying dairy products rolled around 1:50pm.
The driver is not seriously injured but the road may be blocked for some time.
A crane is on its way to move the truck, cleaners are on their way and diversions are being put in place.
Motorists are thanked in advance for their patience.
ENDS